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Contraindications of Vitamin C and Cancer Treatment

Posted by: biologyblog | October 7, 2008 | 3 Comments |



By Rachel B

Vitamin C helps to boost the immune system, and as the weather gets colder many people will be taking in large doses in hopes of avoiding illness. However, researchers at Memorial Sloan-Kettering Cancer Center have found that not only does it help boost the immune system of regular cells, but cancer cells as well. Five different chemotherapy drugs were tested in the laboratory, including a powerful new drug called Gleevec and in each case chemo was not as effective if the cells were exposed to vitamin C, killing 30 to 70 cells fewer.

The Center also implanted cancer cells into mice to study this phenomenon on a more complex level and it was found that tumors in the mice grew much more rapidly if they were exposed to vitamin C. On a cellular level the vitamin appeared to repair damage in a cancer cell’s mitochondria, the energy source of the cell. Normally, if the mitochondria were damaged, it would send out signals to the cell to die, but vitamin C stops this process. Researchers explained that though cancer patients should eat a healthy diet including foods rich in the vitamin, tablets that consist of large doses of vitamin C should be avoided.

I thought this article was really interesting because we all try to get a lot of vitamin C to stay well, but in some cases it ends up doing more damage than help. It related well to class since we went over how the parts of a cell and how they contribute to the overall function of it and about what can go wrong in the ways of irregular cellular growth. This article also had a personal effect since I had an aunt who died of lung cancer and my grandma was treated for breast cancer.

SOURCE:  http://well.blogs.nytimes.com/2008/10/01/vitamin-c-may-interfere-with-cancer-treatment/

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Time and time again we are told to take vitamin C. Recently, however, studies have shown that vitamin C does more harm to cancer cells than good. Vitamin C is taken because it is said to protect healthy cells, nevertheless it has been found that vitamin C is protecting the cancer cells as well. Dr. Mark Heaney performed an experiment with five different chemotherapy drugs on cancer cells. He treated some of the cells with vitamin C, and found the chemotherapy drugs to be less effective on those cells previously treated with vitamin C. A second experiment was performed by injecting mice with cancer cells and cancer cells pretreated with vitamin C. The mice that had the cancer cells pretreated with the vitamin C suffered from a more rapid growth in tumors. Vitamin C is not necessarily bad for you, but should be taken in limited quantity. Eating foods which are rich in vitamin C are healthy. However large doses of the vitamin supplement can be dangerous.
I found this article very intriguing, considering most people believe vitamin C is extremely healthy for you. It was interesting to read how exactly vitamin C works; protecting the mitochondria of a cell, basically saving it from dying. I also found it interesting to learn that vitamin C accumulates more in cancer cells than in normal cells. I wonder what causes this attraction to the cancer cell. All in all I thoroughly enjoyed reading this article and hope to find future articles regarding vitamin C in cancer cells.

[...] Contraindications of Vitamin C and Cancer Treatment By biologyblog This article also had a personal effect since I had an aunt who died of lung cancer and my grandma was treated for breast cancer. SOURCE: http://well.blogs.nytimes.com/2008/10/01/vitamin-c-may-interfere-with-cancer-treatment/ … Biology in Action – http://biologyblog.edublogs.org [...]

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